Treatments are subject to clinical eligibility. Individual results may vary. Your Neuvia clinician will assess your suitability and discuss whether vaginal estradiol is right for you before prescribing.
Vaginal Estradiol Cream
Estradiol 0.01%, 30g
- Same-day prescription review from our clinical partners
- Vaginal dryness clinically shown to improve with local estradiol
- Clinically shown to significantly reduce pain during sex from week 4 onwards
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Treatments are subject to clinical eligibility. Individual results may vary. Your Neuvia clinician will assess your suitability and discuss whether vaginal estradiol is right for you before prescribing.
This is a low-dose estradiol cream applied directly to the vaginal area, formulated to treat local symptoms of menopause — dryness, discomfort, irritation — rather than the whole-body symptoms the gel and patch plans address. Because it works locally, the amount of estrogen that reaches the rest of your body is minimal. Your clinician sets your dosing schedule and confirms whether this treatment alone is right for you, or whether it’s better used alongside a systemic plan.
The cream is applied vaginally using the applicator provided. Most treatment starts with a short daily course to settle symptoms, then steps down to a maintenance schedule of two or three times a week. Your exact routine is set by your clinician based on your symptoms and response. A licensed Neuvia clinician reviews your history before prescribing.
It’s time to feelclose again.
How it works
One cream to get everything back to normal down there
When estrogen drops, vaginal tissue thins, dries out and loses elasticity. That affects more than just sex, it affects your daily comfort, your urinary health, and how you feel in your own body. Vaginal estradiol cream restores that missing estrogen directly to the tissue that needs it for targeted relief.
Say goodbye to dryness & irritation.
Tired of sex feeling like razor blades? Of constant dryness and irritation? Local treatments can ease the symptoms of menopause and perimenopause and get everything back to normal down there.
Enjoy sex again
Vaginal estradiol is clinically shown to reduce pain during sex from week four onwards, helping intimacy feel natural and comfortable again.
A healthier urinary tract
Frequent UTIs, urgency and discomfort when you urinate are often estrogen problems, not just bladder problems.
Reduce dryness & irritation
Have itching, burning and dryness that never seems to go away? Estradiol restores moisture and elasticity to vaginal tissue, with clinically significant improvement from week four.
Localized treatment
Unlike systemic HRT, vaginal estradiol works locally, with minimal absorption into the bloodstream. Which means it’s appropriate even for women who can’t take systemic hormones.
Getting started is simpler than you think
Tell us what’s going on
Tell us your symptoms, your health history, what you’ve already tried. Takes about five minutes.
Share your symptoms
A clinician reviews your case
A licensed Neuvia menopause specialist reviews your case and determines if this treatment is right for you.
Janett Calligher
Licensed Clinician for Neuvia
Specialization
Janett specializes in Menopausal treatment for women, particularly early stage menopause to help rebalance hormones
- Janett has 8 years of work experience
- Specialize in Menopausal treatment
Your prescription is approved
If eligible, your clinician prescribes your plan. You’ll get a clear explanation of what you’re taking and why.
Your package is out for delivery.
201 Royal Oaks BLV, WA 30193
Share your symptoms
Janett Calligher
Licensed Clinician for Neuvia
Specialization
Janett specializes in Menopausal treatment for women, particularly early stage menopause to help rebalance hormones
- Janett has 8 years of work experience
- Specialize in Menopausal treatment
Your package is out for delivery.
201 Royal Oaks BLV, WA 30193
Tell us what’s going on
Tell us your symptoms, your health history, what you’ve already tried. Takes about five minutes.
A clinician reviews your case
A licensed Neuvia menopause specialist reviews your case and determines if this treatment is right for you.
Your prescription is approved
If eligible, your clinician prescribes your plan. You’ll get a clear explanation of what you’re taking and why.
Restore estrogen directly where it’s needed most
Estradiol cream works by delivering estrogen directly to the tissue that needs it. Applied locally, it rebuilds your vaginal lining over several weeks to reduce dryness and make sex comfortable again.
Feel the difference within 4 weeks
For the first two weeks, apply daily. After that, twice a week is all you need. Most women notice less dryness and irritation within four weeks. Pain during sex typically improves by week eight.
- Clinically shown to significantly reduce vaginal dryness from week four onwards.¹
- Clinically shown to significantly reduce pain during sex from week eight onwards.²
- Minimal absorption into the bloodstream. Effective without systemic hormone exposure.³
What the science says
“Greatly improves quality of life for many women”
“Hormone therapy remains the most effective treatment for vasomotor symptoms and the genitourinary syndrome of menopause. Low-dose vaginal estrogen therapy greatly improves quality of life for many women.”The Menopause Society, 2022
Why Neuvia?
Waiting for your doctor isn’t your only option.
Time to first consultation
Menopause specialists
Treatment delivered to your door
HSA/FSA eligible
Available in all 50 states